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26 février 2013

La newsletter de stop-tabac: les sujets clés de l?actualité mondiale sur le tabagisme

Sélection réalisée par Jean-François Etter

Le 26 février 2013

- Le cancer du poumon explose chez les femmes
- Questionnaire pour les les femmes enceintes fumeuses
- Efficacy of cytisine in helping smokers quit: systematic review and meta-analysis
- Chattez avec un médecin tabacologue

Le cancer du poumon explose chez les femmes

Cette maladie devrait devenir le cancer le plus meurtrier chez les femmes européennes d'ici à 2015, selon une étude. Lire la suite:
www.20min.ch/ro/life/lifestyle/story/25323430 (16 02 2013)
(26 02 2013)

Questionnaire pour les les femmes enceintes fumeuses

Un étudiant de maîtrise (Montpellier) réalise une étude sur les femmes enceintes fumeuses. Si c'est votre cas, veuillez prendre quelques minutes pour répondre à un questionnaire en ligne:


Merci de votre participation ! (20 02 2013)
(26 02 2013)

Efficacy of cytisine in helping smokers quit: systematic review and meta-analysis


A recent rigorous study has shown that cytisine, a low-cost drug, is effective for smoking cessation. A number of earlier studies exist, mostly from former communist countries where cytisine has been used since the 1960s. The key question now is whether there is sufficient evidence to warrant licensing cytisine or whether more work is needed. A systematic review was undertaken to assess the efficacy of cytisine in smoking cessation.


The Cochrane Library, CINAHL, Embase, Medline and PsycINFO databases were searched for relevant data. Data from controlled trials were entered into two separate meta-analyses. The first considered the strictest definition of outcome and longest follow-up from all available studies and the second pooled outcomes from studies with biochemically validated abstinence and follow-up of 6 months or longer.


Eight controlled trials were identified. Seven trials provided extractable data and, when pooled (first meta-analysis), produced a risk ratio (RR) of 1.57 (95% CI 1.42 to 1.74). Data from two high-quality studies (second meta-analysis) produced a pooled RR of 3.29 (95% CI 1.84 to 5.90). Patients on cytisine reported more gastrointestinal symptoms than patients on placebo (RR=1.76, 95% CI 1.28 to 2.42). There was no difference in overall reports of adverse events and no specific safety concerns emerged.


Cytisine is an effective treatment for smoking cessation with efficacy comparable to that of other currently licensed treatments. Given its low cost and potential for public health benefit, expedited licensing of cytisine for smoking cessation is warranted.

Thorax. 2013 Feb 12. doi: 10.1136/thoraxjnl-2012-203035. [Epub ahead of print]

Hajek P, McRobbie H, Myers K.

http://thorax.bmj.com/content/early/2013/02/11/thoraxjnl-2012-203035.abstract (25 02 2013)
(26 02 2013)

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